Biological and Biochemical Foundations of Living Systems: Foundational Concept 1

Biomolecules have unique properties that determine how they contribute to the structure and function of cells, and how they participate in the processes necessary to maintain life.

The unique chemical and structural properties of biomolecules determine the roles they play in cells. The proper functioning of a living system depends on the many components acting harmoniously in response to a constantly changing environment. Biomolecules are constantly formed or degraded in response to the perceived needs of the organism.

With these building blocks, medical students will be able to learn how the major biochemical, genetic, and molecular functions of the cell support health and lead to disease.

Content Category 1A: Structure and function of proteins and their constituent amino acids

Category 1A focuses on the structural and functional complexity of proteins, which is derived from their component amino acids, the sequence in which the amino acids are covalently bonded, and the...

Content Category 1B: Transmission of genetic information from the gene to the protein

Category 1B focuses on the molecular mechanisms responsible for the transfer of sequence-specific biological information between biopolymers which ultimately results in the synthesis of proteins.

Content Category 1C: Transmission of heritable information from generation to generation and the processes that increase genetic diversity

Category 1C focuses on the mechanisms that function to transmit the heritable information stored in DNA from generation to generation.

Content Category 1D: Principles of bioenergetics and fuel molecule metabolism

Category 1D focuses on the biomolecules and regulated pathways involved in harvesting chemical energy stored in fuel molecules, which serves as the driving force for all of the processes that take...